Figure 3

ACE2 and TMPRSS2 polymorphisms and the development of COVID-19: a review of the literature

Adrhyan Araújo da Silva Oliveira, Ana Maisa Passos da Silva, Jackson Alves da Silva Queiroz, Paulo Ricardo Freitas de Souza, Juan Miguel Villalobos Salcedo and Deusilene Souza Vieira*

Published: 28 April, 2022 | Volume 6 - Issue 1 | Pages:


Figure 3:

Cleavage of the S protein of SARS-CoV-2 by TMPRSS2. 
Subtitle: 1) Viral particle approaches and interacts with angiotensin-converting enzyme 2 (ACE2); 2) TMPRSS2 cleaves the S2’ subunit of the Spike protein by activating its RBD domain and interacting with ACE2; 3) Fusion of the viral envelope induced by activation of the virus S protein and release of the viral genome into the cytoplasm.

Read Full Article HTML DOI: 10.29328/journal.ijcv.1001044 Cite this Article Read Full Article PDF

More Images

Similar Articles

Recently Viewed

Read More

Most Viewed

Read More